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Tropical fish study offers insight into MS
Findings could have implications for human medicine

Insights gained from a study of tropical fish could improve our understanding of the nervous system, and even enhance the treatment of human conditions such as multiple sclerosis (MS).

By studying zebrafish, scientists at the University of Edinburgh uncovered vital clues about the production of myelin - a fatty sheath that insulates and protects the nerve fibres.

As myelin allows nerve impulses to be transmitted quickly, it is essential for good health. When it breaks down and is not repaired properly, it can lead to the debilitating symptoms of MS.

Zebrafish were used in the study as they share more than 80 per cent of the genes linked to human diseases, and exhibit very similar drug responses to humans. As young zebrafish are transparent, researchers were able to view their living nervous system without invasive surgery.

As a result of the study, scientists were able to quantify the time frame for developing myelin for the first time.

The findings demonstrate that the individual cells in the brain and central nervous system only have a matter of hours in which to generate the protective coating.

Following this, the team at Edinburgh are now investigating the ways in which gene manipulation and drugs could promote myelin generation in zebrafish.

Researcher at the university, Dr David Lyons, said: "To enhance myelin repair, we will need to improve either their ability to make myelin during the short time in which they have to do this, or find a way to allow them to produce myelin for a longer period of time."

The study, which has been published in Developmental Cell, offers hope for future treatments of myelin-related disorders in humans.

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Animal Medicines Amnesty returns this November

News Story 1
 Veterinary practices are being urged to help owners safely dispose of any unused and expired pet medicines - not just antibiotics - during November's Animal Medicines Amnesty.

Organised by the Responsible Use of Medicines Alliance Companion Animal and Equine (RUMA CA&E), the initative is supported by a range of cross-sector organisations.

Practices are encouraged to use the campaign to engage the whole practice team and raise awareness of the safe disposal of medicines with clients. Learn how your practice can get involved at rumacae.org.uk 

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News Shorts
APHA launches free virtual work experience programme

The Animal and Plant Health Agency (APHA), in collaboration with Springpod, has launched a free virtual work experience programme, giving young people across the UK the chance to explore careers dedicated to protecting animal and plant health.

The on-demand programme offers a unique insight into career opportunities within APHA, showcasing how students can contribute to tackling some of the UK's most critical biosecurity and environmental challenges.

Designed for students aged 13 and over, the course includes more than 10 hours of engaging content featuring real-life industry insights, scenario-based challenges, and practical guidance on applying for jobs. To register for the course, visit the APHA website.