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Vaccine for Malignant Catarrhal Fever?
The annual wildebeest migration - one of the world's greatest spectacles but also a real threat to the livelihood of local farms.
The annual migration of over a million wildebeest across the Serengeti and Maasai Mara is often described as one of the greatest spectacles on earth. However, this natural wonder poses a real threat to the livelihood of local farmers whose cattle are essential to their economic and social welfare.

RESEARCHERS led by David Haig, Professor of Animal Infection and Immunity at The University of Nottingham have already developed a candidate MCF vaccine for use in cattle. The next step is to test it in field conditions. Over the next three years his research team will test the vaccine in Tanzania, develop it further as required and then look to make a new vaccine for a sheep virus which is very similar to the wildebeest virus and causes MCF in livestock in other parts of the world, including Europe, Indonesia, Australasia and the Americas.

Professor Haig, from the School of Veterinary Medicine and Science, said: “The quest for a vaccine for Malignant Catarrhal Fever goes back to the middle of the last century. We have the first successful vaccine candidate and this is eagerly sought by the pastoralists and farmers in Eastern and Southern Africa, who have been lobbying for this for many years. We also have a strategy to develop a vaccine for a related virus causing MCF elsewhere in the world and are delighted that BBSRC/DFID have given us the opportunity to develop this.”

The research project is part of a £13m initiative... to support farmers and families in the developing world.
The research project is part of a £13m initiative funded by the Biotechnology and Biological Sciences Research Council (BBSRC) and the Department for International Development (DFID) to support farmers and families in the developing world.

Professor Haig will be working with experts from Glasgow University, the Moredun Research Institute, in Scotland, and Sokoine University of Agriculture in Tanzania, the Tanzania Wildlife Research Institute (TAWIRI), Tanzania National Parks (TANAPA), Central Veterinary Laboratory, and VETAID, Tanzania.

Agriculture is vital for the livelihoods of 75 per cent of the world's poor. Food demand is predicted to increase by 50 per cent by 2030. The BBSRC and DFID have joined forces to harness the UK's world-class bioscience base to address the challenges posed by livestock diseases and work with developing countries to provide practical and sustainable solutions.

‘Combating Infectious Diseases of Livestock for International Development’ is an initiative made up of 16 projects, involving 16 UK institutions and eight other countries, which over the next four years will look at some of the most prevalent, damaging and costly diseases of livestock in developing countries and work with more than 20 overseas institutes to not only control or prevent these diseases but also to build scientific capacity at a local and national level within these countries to enable them to manage these diseases and apply new findings and technologies to other disease areas, in both livestock and humans.

‘Combating Infectious Diseases of Livestock for International Development’ is an initiative made up of 16 projects, involving 16 UK institutions and eight other countries, which will look at some of the most prevalent, damaging and costly diseases of livestock in developing countries.
The projects will also offer significant benefits to farmers and consumers in the UK — animal diseases do not respect national boundaries and are estimated to have cost the UK economy over £15 billion over the past 15 years. Several of the diseases being tackled by the initiative are spreading across countries and continents and some are already a direct threat to UK livestock such as Foot and Mouth disease and Bluetongue virus. New technologies developed as part of this research could also be transferable for use to combat other animal diseases and possibly human ones too.

Science and Innovation Minister Lord Drayson said: “This collaboration demonstrates the UK's determination to share our world-leading science in the search for improved treatments and diagnostic tools in animal health. Animal disease is a deadly threat that leaves no corner of the Earth untouched. This research will allow communities to protect food chains and economies at home and in developing countries.”

By bringing together the best science and the brightest minds from around the globe, the initiative aims to generate workable solutions on the ground to improve animal welfare, productivity and ultimately enhance the lives of millions of people.

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Reporting service for dead wild birds updated

News Story 1
 The Animal and Plant Health Agency (APHA) has updated its online reporting service for dead wild birds.

The new version allows those reporting a dead bird to drop a pin on a map when reporting the location. It also includes a wider range of wild bird species groups to select from when describing the bird.

The online service, which helps APHA to monitor the spread of diseases such as avian influenza, can be accessed here

Click here for more...
News Shorts
NI chief vet urges bluetongue vigilance

Northern Ireland's chief veterinary officer (CVO) has urged farmers to be vigilant for signs of bluetongue, after the Animal and Plant Health Agency warned there was a very high probability of further cases in Great Britain.

There have been 126 confirmed cases of bluetongue virus serotype 3 in England since November 2023, with no cases reported in Northern Ireland. The movement of live ruminants from Great Britain to Northern Ireland is currently suspended.

According to the Department of Agriculture, Environment and Rural Affairs (DAERA), the virus is most likely to enter Northern Ireland through infected animals or germplasm (semen or ova) being imported.

Brian Dooher, Northern Ireland's CVO, said: "Surveillance for this disease within Northern Ireland has been increased to assist with detection at the earliest opportunity which will facilitate more effective control measures."

Farmers should report any suspicions of the disease to their private veterinary practitioner, the DAERA Helpline on 0300 200 7840 or their local DAERA Direct Veterinary Office.